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Fish says she’d take the vaccine herself if she could get a hold of it, and even wonders whether it’s ethical to withhold its potential benefits from trial subjects in the placebo arm.But Netea says the randomized design is critical: “Otherwise we would never know if this is good for people.” The team may have answers within a few months.Jop de Vrieze is a science journalist in Amsterdam. Kwangmoozaa/iStock

A century-old tuberculosis vaccine, bacillus Calmette-Guerin, or BCG vaccine, could...
23, 2020 , 6:25 AM.

They will test whether a century-old vaccine against tuberculosis (TB), a bacterial disease, can rev up the human immune system in a broad way, allowing it to better fight the virus that causes coronavirus disease 2019 and, perhaps, prevent infection with it altogether. The study, conducted by … We've received your submission.Coronavirus death rates are nearly six times lower in countries that use a nearly century-old tuberculosis vaccine, The study, conducted by researchers at the Johns Hopkins Bloomberg School of Public Health, found that the COVID-19 mortality rate among countries that use the Bacillus Calmette-Guérin (BCG) vaccination was 5.8 times lower than in those that do not.“Demonstration that exposure to BCG vaccination can ameliorate severe COVID-19 disease and lower mortality could rationalize a therapeutic or preventive strategy that can have immediately deployable global impact,” the researchers wrote.“Therefore, using existing publicly available data, we examined at the ecological level whether country-level COVID-19 mortality was associated with BCG use in national immunization schedules.”The vaccine, first administered to a human in 1921 and primarily used to protect against tuberculosis, is undergoing clinical trials to test its ability to ward off COVID-19.Using the mortality per 1 million residents of each country with sufficient data, researchers estimated the coronavirus fatality rate from the 50 countries with the highest number of cases.After accounting for the economic status of the countries and their elderly populations — both of which contribute to death rates — “the intriguing observation of a significant association between BCG use and lower COVID-19-attributable mortality remained discernable,” the researchers said.The researchers said the findings “warrant deeper epidemiological scrutiny and prospective evaluation in individually randomized trials.”The WHO will “evaluate the evidence when it is available,” and does not currently recommend the vaccination for the prevention of COVID-19, it said.Studies like the Johns Hopkins one, which has yet to be peer-reviewed, “are prone to significant bias from many confounders, including differences in national demographics and disease burden, testing rates for COVID-19 virus infections, and the stage of the pandemic in each country,” the organization said.Researchers at the Murdoch Children’s Research Institute in Melbourne, Australia, “I think BCG vaccine is a bit of the equivalent of a Hail Mary pass,” Dr. William Schaffner, an infectious disease specialist at the Vanderbilt University School of Medicine,

An early study, that's not yet peer-reviewed, says countries that require the vaccine are seeing lower COVID-19 death tolls. Behind Ellen DeGeneres' spectacular fall from graceMan plants mystery seeds from China — here’s what happenedGangbanger carried out 3 drive-bys after he was freed without bail: prosecutorsCuomo begs the rich to return to NYC: 'Come over, I'll cook!

Looking at absenteeism has the advantage that any beneficial effects of the BCG vaccine on influenza and other infections may be captured as well, he says.Although the study is randomized, participants will likely know if they got the vaccine instead of a placebo. The studies will be done in physicians and nurses, who are at higher risk of becoming infected with the respiratory disease than the general population, and in the elderly, who are at higher risk of serious illness if they become infected.A team in the Netherlands will kick off the first of the trials this week. If these cells fail, they call in the “adaptive” immune system, and T cells and antibody-producing B cells start to divide to join the fight.
Since then, the clinical evidence has strengthened and several groups have made important steps investigating how BCG may generally boost the immune system. Philip Supply holds the original test tube used to develop the BCG vaccine.At death's door: Photo shows firefighters trying to get into warehouse just before Beirut blast

''F--king bulls--t': Yankees coach loses it on despised umpireDr. Thanks for contacting us. Coronavirus death rates are nearly six times lower in countries that use a nearly century-old tuberculosis vaccine, a new study found. And a team at the Max Planck Institute for Infection Biology last week announced that—inspired by Netea’s work—it will embark on Eleanor Fish, an immunologist at the of the University of Toronto, says the vaccine probably won’t eliminate infections with the new coronavirus completely, but is likely to dampen its impact on individuals. Sorry, your blog cannot share posts by email. Ziekenhuizen doen proef met tbc-vaccin als bescherming tegen corona 18 maart 2020 08:11 18-03-20 08:11 Laatste update: 18 maart 2020 19:50 Update: 18-03-20 19:50 507 NUjij-reacties reacties